KLF4 anticorps (AA 20-53)
Aperçu rapide pour KLF4 anticorps (AA 20-53) (ABIN3031573)
Antigène
Voir toutes KLF4 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 20-53
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Purification
- Purified
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Immunogène
- A portion of amino acids 20-53 from the human protein was used as the immunogen for this KLF4 antibody.
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Isotype
- Ig Fraction
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Indications d'application
- Titration of the KLF4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Aliquot the KLF4 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- KLF4 (Kruppel-Like Factor 4 (Gut) (KLF4))
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Autre désignation
- KLF4
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Sujet
- Kruppel-like factor 4 (KLF4) is a transcription factor involved in both proliferation and differentiation in the colon. It is down-regulated in both mouse and human colonic adenomas and has been implicated as a tumor suppressor in the gut, whereas in breast cancer, KLF4 is an oncogene. KLF4 is also involved in reprogramming differentiated cells into pluripotent stem cells. KLF4 can act as a transcriptional activator or repressor, but the underlying mechanisms are poorly understood.
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UniProt
- O43474
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Pathways
- Peptide Hormone Metabolism, Stem Cell Maintenance
Antigène
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